Nepalese mountaineer Nirmal Purja, American biochemist Jennifer Doudna and other modern-day achievers, both famous and more obscure, started with big, bold dreams. Dreams that seemed unlikely, difficult, and perhaps even impossible. Yet, they persisted. They envisioned success, devised intentional plans, and set to work. How can we be inspired by their stories to reach beyond the apparent odds and move towards fulfilling our own intentions and dreams?